Primera División - Apertura 2021
| Pos | Club | PJ | G | E | P | GD | PTS |
|---|---|---|---|---|---|---|---|
| 1 |  Atl. San Jorge | 14 | 8 | 5 | 1 | 28 | 29 |
| 2 |  La Emilia | 14 | 9 | 2 | 3 | 12 | 29 |
| 3 |  Gral. San Martin | 14 | 7 | 5 | 2 | 10 | 26 |
| 4 |  A. Sastre | 14 | 8 | 2 | 4 | 3 | 26 |
| 5 |  El Expreso | 14 | 7 | 4 | 3 | 9 | 25 |
| 6 |  San Martin (CP) | 14 | 7 | 3 | 4 | 0 | 24 |
| 7 |  Americano | 14 | 6 | 5 | 3 | 7 | 23 |
| 8 |  Trebolense | 14 | 6 | 2 | 6 | -1 | 20 |
| 9 |  Juv. Unida | 14 | 5 | 3 | 6 | -1 | 18 |
| 10 |  Dep. Mitre | 14 | 3 | 6 | 5 | 2 | 15 |
| 11 |  A. y D. Piamonte | 14 | 3 | 6 | 5 | -3 | 15 |
| 12 |  Union (Sastre) | 14 | 4 | 3 | 7 | -12 | 15 |
| 13 |  Juv. Guadalupe | 14 | 3 | 3 | 8 | -18 | 12 |
| 14 |  Susanense | 14 | 2 | 1 | 11 | -16 | 7 |
| 15 |  Union (LC) | 14 | 1 | 2 | 11 | -20 | 5 |